Use below expression in derived column (if used)...

REPLICATE("0",16 - LEN([Column0])) + [Column0]

here,change "Column0" with your column name.

Hi Sandeep, i have another problem My source : Flat files Target : Sybase and datatype is Numeric(20,3)

i cant do this calculation in SSIS
((dt_numeric,20,3)SUBSTRING(STRING,44,11)) / 1000 when running SSIS job, am getting this error: [ADO NET Destination [1057]] Error: An exception has occurred during data insertion, the message returned from the provider is: [ZZZZZ] [Message Class: 16] [Message State: 1] [Transaction State: 0] [Server Name: imalrep] [Native Code: 245] [ASEOLEDB]Domain error during implicit conversion of NUMERIC value '' to a NUMERIC field. [ZZZZZ] [Message Class: 10] [Message State: 0] [Transaction State: 3] [Server Name: imalrep] [Native Code: 3622] [ASEOLEDB]Domain error occurred.